Self-Tuning at Large (Distances): 4D Description of Runaway Dilaton Capture

We complete here a three-part study (see also arXiv:1506.08095 and 1508.00856) of how codimension-two objects back-react gravitationally with their environment, with particular interest in situations where the transverse `bulk' is stabilized by the interplay between gravity and flux-quantization in a dilaton-Maxwell-Einstein system such as commonly appears in higher-dimensional supergravity and is used in the Supersymmetric Large Extra Dimensions (SLED) program. Such systems enjoy a classical flat direction that can be lifted by interactions with the branes, giving a mass to the would-be modulus that is smaller than the KK scale. We construct the effective low-energy 4D description appropriate below the KK scale once the transverse extra dimensions are integrated out, and show that it reproduces the predictions of the full UV theory for how the vacuum energy and modulus mass depend on the properties of the branes and stabilizing fluxes. In particular we show how this 4D theory learns the news of flux quantization through the existence of a space-filling four-form potential that descends from the higher-dimensional Maxwell field. We find a scalar potential consistent with general constraints, like the runaway dictated by Weinberg's theorem. We show how scale-breaking brane interactions can give this potential minima for which the extra-dimensional size, $\ell$, is exponentially large relative to underlying physics scales, $r_B$, with $\ell^2 = r_B^2 e^{- \varphi}$ where $-\varphi \gg 1$ can be arranged with a small hierarchy between fundamental parameters. We identify circumstances where the potential at the minimum can (but need not) be parametrically suppressed relative to the tensions of the branes, provide a preliminary discussion of the robustness of these results to quantum corrections, and discuss the relation between what we find and earlier papers in the SLED program.Comment: 37 pages + appendice

The Gravity of Dark Vortices: Effective Field Theory for Branes and Strings Carrying Localized Flux

A Nielsen-Olesen vortex usually sits in an environment that expels the flux that is confined to the vortex, so flux is not present both inside and outside. We construct vortices for which this is not true, where the flux carried by the vortex also permeates the `bulk' far from the vortex. The idea is to mix the vortex's internal gauge flux with an external flux using off-diagonal kinetic mixing. Such `dark' vortices could play a phenomenological role in models with both cosmic strings and a dark gauge sector. When coupled to gravity they also provide explicit ultra-violet completions for codimension-two brane-localized flux, which arises in extra-dimensional models when the same flux that stabilizes extra-dimensional size is also localized on space-filling branes situated around the extra dimensions. We derive simple formulae for observables such as defect angle, tension, localized flux and on-vortex curvature when coupled to gravity, and show how all of these are insensitive to much of the microscopic details of the solutions, and are instead largely dictated by low-energy quantities. We derive the required effective description in terms of a world-sheet brane action, and derive the matching conditions for its couplings. We consider the case where the dimensions transverse to the bulk compactify, and determine how the on- and off-vortex curvatures and other bulk features depend on the vortex properties. We find that the brane-localized flux does not gravitate, but just renormalizes the tension in a magnetic-field independent way. The existence of an explicit UV completion puts the effective description of these models on a more precise footing, verifying that brane-localized flux can be consistent with sensible UV physics and resolving some apparent paradoxes that can arise with a naive (but commonly used) delta-function treatment of the brane's localization within the bulk.Comment: 36 pages + appendices, 7 figure

EFT for Vortices with Dilaton-dependent Localized Flux

We study how codimension-two objects like vortices back-react gravitationally with their environment in theories (such as 4D or higher-dimensional supergravity) where the bulk is described by a dilaton-Maxwell-Einstein system. We do so both in the full theory, for which the vortex is an explicit classical `fat brane' solution, and in the effective theory of `point branes' appropriate when the vortices are much smaller than the scales of interest for their back-reaction (such as the transverse Kaluza-Klein scale). We extend the standard Nambu-Goto description to include the physics of flux-localization wherein the ambient flux of the external Maxwell field becomes partially localized to the vortex, generalizing the results of a companion paper to include dilaton-dependence for the tension and localized flux. In the effective theory, such flux-localization is described by the next-to-leading effective interaction, and the boundary conditions to which it gives rise are known to play an important role in how (and whether) the vortex causes supersymmetry to break in the bulk. We track how both tension and localized flux determine the curvature of the space-filling dimensions. Our calculations provide the tools required for computing how scale-breaking vortex interactions can stabilize the extra-dimensional size by lifting the dilaton's flat direction. For small vortices we derive a simple relation between the near-vortex boundary conditions of bulk fields as a function of the tension and localized flux in the vortex action that provides the most efficient means for calculating how physical vortices mutually interact without requiring a complete construction of their internal structure. In passing we show why a common procedure for doing so using a $\delta$-function can lead to incorrect results. Our procedures generalize straightforwardly to general co-dimension objects.Comment: 45 pages + appendix, 6 figure

Adherence to secondary stroke prevention strategies - Results from the German stroke data bank

Only very limited data are available concerning patient adherence to antithrombotic medication intended to prevent a recurrent stroke. Reduced adherence and compliance could significantly influence the effects of any stroke prevention strategies. This study from a large stroke data bank provides representative data concerning the rate of stroke victims adhering to their recommended preventive medication. During a 2-year period beginning January 1, 1998, all patients with acute stroke or TIA in 23 neurological departments with an acute stroke unit were included in the German Stroke Data Bank. Data were collected prospectively, reviewed, validated and processed in a central data management unit. Only 12 centers with a follow-up rate of 80% or higher were included in this evaluation. 3,420 patients were followed up after 3 months, and 2,640 patients were followed up one year after their stroke. After one year, 96% of all patients reported still adhere to at least one medical stroke prevention strategy. Of the patients receiving aspirin at discharge, 92.6% reported to use that medication after 3 months and 84% after one year, while 81.6 and 61.6% were the respective figures for clopidogrel, and 85.2 and 77.4% for oral anticoagulation. Most patients who changed medication switched from aspirin to clopidogrel. Under the conditions of this observational study, adherence to stroke prevention strategies is excellent. The highest adherence rate is noticed for aspirin and oral anticoagulation. After one year, very few patients stopped taking stroke preventive medication. Copyright (C) 2003 S. Karger AG, Basel

Cryogenic Calibration Setup for Broadband Complex Impedance Measurements

Reflection measurements give access to the complex impedance of a material on a wide frequency range. This is of interest to study the dynamical properties of various materials, for instance disordered superconductors. However reflection measurements made at cryogenic temperature suffer from the difficulty to reliably subtract the circuit contribution. Here we report on the design and first tests of a setup able to precisely calibrate in situ the sample reflection, at 4.2 K and up to 2 GHz, by switching and measuring, during the same cool down, the sample and three calibration standards.Comment: (6 pages, 6 figures

Influence of age on outcome from thrombolysis in acute stroke: a controlled comparison in patients from the Virtual International Stroke Trials Archive (VISTA)

<p><b>Background and Purpose:</b> Thrombolysis for acute ischemic stroke in patients aged >80 years is not approved in some countries due to limited trial data in the very elderly. We compared outcomes between thrombolysed and nonthrombolysed (control) patients from neuroprotection trials to assess any influence of age on response.</p> <p><b>Method:</b>Among patients with ischemic stroke of known age, pretreatment severity (baseline National Institutes of Health Scale Score), and 90-day outcome (modified Rankin Scale score; National Institutes of Health Scale score), we compared the distribution of modified Rankin score in thrombolysed patients with control subjects by Cochran-Mantel-Haenszel test and then logistic regression after adjustment for age and baseline National Institutes of Health Scale score. We examined patients ≤80 and ≥ 81 years separately and then each age decile.</p> <p><b>Results:</b> Rankin data were available for 5817 patients, 1585 thrombolysed and 4232 control subjects; 20.5% were aged >80 years (mean ± SD, 85.1 ± 3.4 years). Baseline severity was higher among thrombolysed than control subjects (median National Institutes of Health Scale score 14 versus 13, P<0.05). The distribution of modified Rankin Scale scores was better among thrombolysed patients (P<0.0001; OR, 1.39; 95% CI, 1.26 to 1.54). The association occurred independently with similar magnitude among young (P<0.0001; OR, 1.42; 95% CI, 1.26 to 1.59) and elderly (P=0.002; OR, 1.34; 95% CI, 1.05 to 1.70) patients. ORs were consistent across all age deciles >30 years; outcomes assessed by National Institutes of Health Scale score gave supporting significant findings, and dichotomized modified Rankin Scale score outcomes were also consistent.</p> <p><b>Conclusions:</b> Outcome after thrombolysis for acute ischemic stroke was significantly better than in control subjects. Despite the expected poorer outcomes among elderly compared with young patients that is independent of any treatment effect, the association between thrombolysis treatment and improved outcome is maintained in the very elderly. Age alone should not be a barrier to treatment.</p&gt

Accelerated motion and the self-force in Schwarzschild spacetime

We provide expansions of the Detweiler-Whiting singular field for motion along arbitrary, planar accelerated trajectories in Schwarzschild spacetime. We transcribe these results into mode-sum regularization parameters, computing previously unknown terms that increase the convergence rate of the mode-sum. We test our results by computing the self-force along a variety of accelerated trajectories. For non-uniformly accelerated circular orbits we present results from a new 1+1D discontinuous Galerkin time-domain code which employs an effective-source. We also present results for uniformly accelerated circular orbits and accelerated bound eccentric orbits computed within a frequency-domain treatment. Our regularization results will be useful for computing self-consistent self-force inspirals where the particle's worldline is accelerated with respect to the background spacetime.Comment: 19 pages, 6 figures (accepted CQG special issue article version

Hypervelocity binary stars: smoking gun of massive binary black holes

The hypervelocity stars recently found in the Galactic halo are expelled from the Galactic center through interactions between binary stars and the central massive black hole or between single stars and a hypothetical massive binary black hole. In this paper, we demonstrate that binary stars can be ejected out of the Galactic center with velocities up to 10^3 km/s, while preserving their integrity, through interactions with a massive binary black hole. Binary stars are unlikely to attain such high velocities via scattering by a single massive black hole or through any other mechanisms. Based on the above theoretical prediction, we propose a search for binary systems among the hypervelocity stars. Discovery of hypervelocity binary stars, even one, is a definitive evidence of the existence of a massive binary black hole in the Galactic center.Comment: 5 pages, 3 figures, shortened version, ApJL in pres

Dynamical mean-field equations for strongly interacting fermionic atoms in a potential trap

We derive a set of dynamical mean-field equations for strongly interacting fermionic atoms in a potential trap across a Feshbach resonance. Our derivation is based on a variational ansatz, which generalizes the crossover wavefunction to the inhomogeneous case, and the assumption that the order parameter is slowly varying over the size of the Cooper pairs. The equations reduce to a generalized time-dependent Gross-Pitaevskii equation on the BEC side of the resonance. We discuss an iterative method to solve these mean-field equations, and present the solution for a harmonic trap as an illustrating example to self-consistently verify the approximations made in our derivation.Comment: replaced with the published versio